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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23B
All Species:
28.18
Human Site:
S228
Identified Species:
51.67
UniProt:
Q15437
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15437
NP_006354.2
767
86479
S228
P
Q
E
H
P
F
A
S
S
R
F
L
Q
P
V
Chimpanzee
Pan troglodytes
XP_001140754
767
86435
S228
P
Q
E
H
P
F
V
S
S
R
F
L
Q
P
V
Rhesus Macaque
Macaca mulatta
XP_001091771
765
86128
S226
Q
V
Q
Q
P
P
P
S
N
R
F
L
Q
P
V
Dog
Lupus familis
XP_534332
767
86392
S228
P
Q
E
H
P
F
V
S
S
R
F
L
Q
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D662
767
86419
S228
P
Q
E
Q
P
F
V
S
S
R
F
L
Q
P
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513018
765
86087
S226
Q
V
Q
Q
P
P
P
S
N
R
F
L
Q
P
V
Chicken
Gallus gallus
Q5ZK03
767
86285
S228
A
P
E
Q
P
V
I
S
S
R
F
L
Q
P
V
Frog
Xenopus laevis
NP_001086405
741
83183
S228
P
Q
E
Q
P
F
L
S
S
R
F
L
Q
P
V
Zebra Danio
Brachydanio rerio
Q7SZE5
765
86062
S226
Q
Q
P
Q
V
P
P
S
N
R
F
L
Q
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392515
768
85881
A229
G
G
Q
P
L
P
A
A
N
R
F
L
Q
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780042
764
86244
M227
Q
Q
P
Q
Q
P
P
M
N
K
F
L
Q
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15303
768
85366
L224
N
K
V
T
P
F
S
L
N
R
F
F
L
P
L
Red Bread Mold
Neurospora crassa
Q9C284
775
86260
A230
R
P
F
P
A
G
P
A
S
R
F
L
L
P
V
Conservation
Percent
Protein Identity:
100
99.4
84.7
97.6
N.A.
97.1
N.A.
N.A.
84.7
93
88.6
85.5
N.A.
N.A.
73.5
N.A.
75.8
Protein Similarity:
100
99.6
92.5
98.9
N.A.
98.5
N.A.
N.A.
92.4
96.6
92.1
91.6
N.A.
N.A.
85.4
N.A.
85.6
P-Site Identity:
100
93.3
53.3
93.3
N.A.
80
N.A.
N.A.
53.3
66.6
86.6
53.3
N.A.
N.A.
46.6
N.A.
40
P-Site Similarity:
100
93.3
66.6
93.3
N.A.
86.6
N.A.
N.A.
66.6
66.6
86.6
60
N.A.
N.A.
66.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51
57.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
68.2
71.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
16
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
47
0
0
0
0
100
8
0
0
0
% F
% Gly:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
8
8
0
0
0
93
16
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% N
% Pro:
39
16
16
16
70
39
39
0
0
0
0
0
0
100
0
% P
% Gln:
31
54
24
54
8
0
0
0
0
0
0
0
85
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
93
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
70
54
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
16
8
0
8
8
24
0
0
0
0
0
0
0
85
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _